- Mildronate 500
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Mildronate 500
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Item # 6539582

  • Sports Memorabilia
  • toms1234
  • New
  • 26/9/2017
  • 24/10/2017
  • 46
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Meldonium, trade-named as Mildronate among others, is a limited-market pharmaceutical, developed in 1970 by Ivars Kalviņš at the USSR Latvia Institute of Organic Synthesis, and now manufactured by the Latvian pharmaceutical company Grindeks and several generic manufacturers. It is primarily distributed in Eastern European countries as an anti-ischemia medication.

Meldonium is manufactured by Grindeks, a Latvian pharmaceutical company, with offices in thirteen Eastern European countries
Mildronate is a structural analogue of gamma-butyrobetaine, a substance contained in every cell of the human body. Mildronate restores the balance between oxygen supply and demand in cells, and removes toxic metabolic products accumulated in cells protecting them from damage. It also possesses an invigorating stimulant effect. Oxygen delivery and utilization by both muscle & brain cells is enhanced.

Meldonium shifts the metabolism, so that it is geared more towards carbohydrate metabolism than fat metabolism. Using carbohydrate as a fuel requires less oxygen to produce energy, so this change can be beneficial in low oxygen conditions. In heart disease, the heart muscle is deprived of oxygen, and the effects of meldonium have been shown to be very beneficial in this disease state. There is also evidence to suggest that meldonium could be equally beneficial under the low oxygen conditions induced by intense endurance exercise.
One review of the effects of meldonium on exercise performance listed the following benefits:
• Decreased levels of lactate and urea in blood
• Improved economy of glycogen: level of glycogen increased in the cells during the long-lasting exercise
• Increased endurance properties and aerobic capabilities of athletes
• Improved functional parameters of heart activity
• Increased physical work capabilities
• Increased rate of recovery after maximal and sub-maximal loads
• Activates CNS functions and protects against stress
• Improves Mental Processes (Memory, Learning, Focus, Concentration, Processing of Information)
• Reduces Fatigue, Increases Motivation & Alertness
• Improves Athletic Training & Competitive Performance
• Improves Microcirculation & Oxygen Delivery

• Meldonium is the leading agent of the cardiovascular group, antiischemic agent of a metabolic action:
Acts as antiischemic cell protector in patients with angina pectoris, chronic heart failure, brain circulation disorders.
Improves physical capacity and mental function in the case of ischemia and in healhty people.

Due to its unique mechanism of action Meldonium, depending on the prescribed dose, is widely used for the treatment of different heart and vascular diseases,

as well as for the improvement of work capacity of healthy people at physical and mental overloads and during rehabilitation period.
Mildronate is one of Latvia's most exported products.

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